WebMar 25, 2024 · In Caenorhabditis elegans, the binding of Piwi protein to a non-coding RNA form, called piRNA, has been found to be important to both reproductive and aging processes. As the biosynthesis of piRNA is modulated by mitochondrial function, it is likely that the interaction between mitochondrial function and piRNA expression plays an … WebAug 4, 2024 · P-element–induced wimpy testis (PIWI)–interacting RNAs (piRNAs) are a subgroup of small noncoding RNAs that are found abundantly in germ cells and are essential for spermatogenesis. 3 The function...
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WebMay 29, 2014 · This piRNA is produced from a piRNA precursor which we named Fem. Fem sequences were arranged in tandem in the sex-determining region of the W chromosome. Inhibition of Fem-derived piRNA-mediated signalling in female embryos led to the production of the male-specific splice variants of B. mori doublesex (Bmdsx), a gene … WebAug 18, 2014 · The model suggests that the piRNA biogenesis pathway is an adaptive system that silences active transposons with sequences complementary to piRNA … simulate flowchart
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